USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TWF1_HUMAN USC-OGP 2-DE database:  TWF1_HUMAN TWF1_HUMAN General information about the entry View entry in simple text format Entry name TWF1_HUMAN Primary accession number Q12792 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Twinfilin-1; AltName: Full=Protein A6; AltName: Full=Protein tyrosine kinase 9;. Gene name Name=TWF1 Synonyms=PTK9 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0430: pI=6.24; Mw=40313 Cross-references UniProtKB/Swiss-Prot Q12792; TWF1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TWF1_HUMAN Primary accession number Q12792 Secondary accession number(s) A8K5A8 B3KXS6 B4DLX9 Q59G07 Q5U0B1 Q6FHJ1 Q6FHL6 Q6NUK9 Q86XL6 Q8TCD3 Sequence was last modified on  September 22, 2009 (version 3) Annotations were last modified on  March 15, 2017 (version 155) Name and origin of the protein Description RecName: Full=Twinfilin-1; AltName: Full=Protein A6; AltName: Full=Protein tyrosine kinase 9; Gene name Name=TWF1 Synonyms=PTK9 Encoded on Name=TWF1; Synonyms=PTK9 Keywords Acetylation; Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U02680; AAC50062.1; -; mRNA EMBL AK127868; BAG54588.1; -; mRNA EMBL AK291223; BAF83912.1; -; mRNA EMBL AK297206; BAG59691.1; -; mRNA EMBL CR541736; CAG46536.1; -; mRNA EMBL CR541761; CAG46561.1; -; mRNA EMBL BT019691; AAV38497.1; -; mRNA EMBL AB209302; BAD92539.1; ALT_INIT; mRNA EMBL BC022344; AAH22344.1; -; mRNA EMBL BC043148; AAH43148.2; ALT_INIT; mRNA EMBL BC068548; AAH68548.1; ALT_INIT; mRNA CCDS CCDS31780.2; -. [Q12792-2]; . CCDS CCDS55818.1; -. [Q12792-3]; . PIR A55922; A55922; . RefSeq NP_001229326.1; NM_001242397.1. [Q12792-3]; . RefSeq NP_002813.3; NM_002822.4. [Q12792-2]; . UniGene Hs.189075; -; . UniGene Hs.313056; -; . ProteinModelPortal Q12792; -; . SMR Q12792; -; . BioGrid 111723; 58; . IntAct Q12792; 28; . MINT MINT-3026525; -; . STRING 9606.ENSP00000449428; -; . iPTMnet Q12792; -; . PhosphoSitePlus Q12792; -; . BioMuta TWF1; -; . DMDM 259016376; -; . OGP Q12792; -; . EPD Q12792; -; . PaxDb Q12792; -; . PeptideAtlas Q12792; -; . PRIDE Q12792; -; . DNASU 5756; -; . Ensembl ENST00000395510; ENSP00000378886; ENSG00000151239. [Q12792-2]; . Ensembl ENST00000548315; ENSP00000449428; ENSG00000151239. [Q12792-3]; . Ensembl ENST00000552521; ENSP00000448750; ENSG00000151239. [Q12792-4]; . GeneID 5756; -; . KEGG hsa:5756; -; . UCSC uc001roa.4; human. [Q12792-2]; . CTD 5756; -; . DisGeNET 5756; -; . GeneCards TWF1; -; . HGNC HGNC:9620; TWF1; . HPA HPA018116; -; . MIM 610932; gene; . neXtProt NX_Q12792; -; . OpenTargets ENSG00000151239; -; . PharmGKB PA162407406; -; . eggNOG KOG1747; Eukaryota; . eggNOG ENOG410XS1J; LUCA; . GeneTree ENSGT00530000063868; -; . HOVERGEN HBG000848; -; . InParanoid Q12792; -; . KO K08870; -; . OMA YDYLQFR; -; . OrthoDB EOG091G0BWK; -; . PhylomeDB Q12792; -; . TreeFam TF352598; -; . GeneWiki TWF1; -; . GenomeRNAi 5756; -; . PRO PR:Q12792; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000151239; -; . ExpressionAtlas Q12792; baseline and differential; . Genevisible Q12792; HS; . GO GO:0015629; C:actin cytoskeleton; ISS:UniProtKB; . GO GO:0005911; C:cell-cell junction; ISS:BHF-UCL; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0030175; C:filopodium; ISS:BHF-UCL; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0030016; C:myofibril; ISS:BHF-UCL; . GO GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL; . GO GO:0032587; C:ruffle membrane; IEA:Ensembl; . GO GO:0003785; F:actin monomer binding; ISS:BHF-UCL; . GO GO:0005524; F:ATP binding; IDA:BHF-UCL; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0005546; F:phosphatidylinositol-4; 5-bisphosphate binding; ISS:BHF-UCL GO GO:0051016; P:barbed-end actin filament capping; IEA:Ensembl; . GO GO:0030837; P:negative regulation of actin filament polymerization; ISS:BHF-UCL; . GO GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL; . GO GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL; . Gene3D 3.40.20.10; -; 2; . InterPro IPR002108; ADF-H; . InterPro IPR029006; ADF-H/Gelsolin-like_dom; . InterPro IPR028458; Twinfilin; . PANTHER PTHR13759; PTHR13759; 1; . Pfam PF00241; Cofilin_ADF; 2; . SMART SM00102; ADF; 2; . PROSITE PS51263; ADF_H; 2; .

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